Overview
Iis listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health
(NIH). This means that Kostmann disease, or a subtype of Kostmann disease
Symptoms of Kostmann disease
Some of the symptoms of Kostmann disease incude:
- Premature tooth loss
- Gum infections
- Frequent bacterial infections
- Fever
- Mouth ulcers
Treatment
Medical Care
- Treating Kostmann disease with prophylactic antibiotics may be considered but are not usually required (see Medication).
- Granulocyte colony stimulating factor (G-CSF) is administered to stimulate neutrophil production (see Medication). Ninety percent of cases respond with increased neutrophil count and less infections. Some patients need doses of as much as 120 μ g/kg.
- Therapy with steroids and testosterone is not effective.
Surgical Care
- Drain abscess as needed.
- Splenectomy is not effective.
- Consider bone marrow transplantation only in patients unresponsive to therapy with G-CSF or in those with leukemic transformation.
Consultations
- Pediatric immunologist
- Pediatric hematologist
For more information, medical assessment and medical quote
as email attachment to
Email : - info@wecareindia.com
Contact Center Tel. (+91) 9029304141 (10 am. To 8 pm. IST)
(Only for international patients seeking treatment in India)
Neurology 
Laparoscopic appendectomy
Laparoscopic orchiopexy
Coronary 
Kasai Procedure
Splenectomy 
