Overview
When is the autologous cartilage cell transplantation a promising method?
For some cases is consistent with the autologous chondrocyte implantation is a promising method in the laboratory bred cartilage cells transplanted from. Since the implanted material has similar biomechanical properties as the natural cartilage has, it is not absorbed by the body sees as foreign. The living chondrocytes are in a position to return for the establishment of a functioning cartilage layer them. As a rule, already after a few weeks, new cartilage tissue formed. To this tissue to be preserved even in the long term, it is necessary accompanying injuries and abnormal by Achsfehlstellungen be included.
Who is for an autologous cartilage transplantation for?
The possibility of a cartilage transplantation (transplantation of cartilage cells) is limited. Before a therapeutic decision must be clarified whether a low-invasive procedure with einzeitigem approach is preferable. With an autologous cartilage cell transplantation in a first meeting cartilage cells collected and then cultured in a special laboratory for a period of 4-8 weeks re-implanted.
Ideally suited for the method:
- Patients under 40 years
- National standing of the ankle cartilage damage
- Damage to the cartilage damage size of 1.5 cm2
It is important to continue the consideration of multiple mobilities in the ankle (ankle instabilities) or Achsfehlstellungen the leg. These must be treated simultaneously to Einheilen of cartilage cells ever to be able to achieve.
What alternatives are there for autologous cartilage cell transplant?
The potential cartilage damage with knochenmarkstimmulierenden or methods such as Knochenanbohrung Mikrofrakturierung (Microfracturing) to deal with are limited. In the upper ankle joint, these methods for damage under a qcm and centered on anklebone able to use. The faserknorpelige replacement tissues, however, has a low durability against mechanical stress. It uses a special instrument to the bone below the damaged cartilage anzufrischen. This is done by taking in one of certain depth. When drilling creates heat that may damage the bone and the formation of cartilage replacement should obstruct.
Prevention
- Regular exercise tones up muscles and joints. Well developed muscles can prevent joint injury after an accident and can lead to early recovery from an operation. In combination with a proper diet, exercise can lower body weight
- Diet- Obese with knee pain can benefit from weight loss. Soya, low fat milk, fruits and vegetables, berries, fiber lead to weight loss. However over a long time, people tend to loose interest and weight lost tends to be regained. Thus diet cannot play an important role in the long run.
- Alcohol abuse and fatty foods are to be avoided.
- Nutritional supplements like Glucosamine comes to the rescue of younger patients.
Surgical treatment
They are available to treat early cartilage lesions. They can be done arthroscopically or by an open method. Drilling, abrasion, cartilage transfer from the unaffected part of the joint can be accomplished arthroscopically.
Cartilage Arthroscopic microfracture and Mosaicplasty are two techniques to repair localized small cartilage defects.
A new procedure is to be introduced in Chennai for young patients. This is called autologous cartilage cell transplant. Young & active patients with a post traumatic cartilage defect measuring about 2- 8cm will be the ideal candidates. Older patients with degenerative changes will do better with a joint replacement.
In this procedure, cartilage cells are obtained from the healthy part of a joint and sent to a laboratory. The cells are cultured in the lab wherein the cell count is multiplied several million times. These cells are returned to the surgeon. He re-implants these cells into the defect and closes the joint. The cells synthesize normal articular cartilage in the defective area. It is recommended for lesions.
Ligament and meniscal injuries should be treated to prevent early osteoarthritis. ACL reconstruction is recommended to prevent further damage to the menisci in people with a torn anterior cruciate ligament. Meniscal suture of torn menisci is possible if done early and the tear occurs in a vascularised (with a blood supply) of the meniscus.
Meniscal transplant is a new technique that can substitute the damaged menisci with cadaveric menisci. This procedure is to be to offered to young patients with an ACL injury and concomitant meniscal injury where the torn meniscus has been removed. This surgery will postpone the onset of osteoarthritis.
Osteotomy If congenital or acquired bony mal-alignment is present then osteotomy can restore normal alignment. In osteotomy either a wedge of bone is removed from the convex side of a deformed leg or a wedge is created on the concave side of the bent leg. An osteotomy alters the line of abnormal load bearing thus preventing the progression of osteoarthritis.
A corrective osteotomy of the knee relieves pain in middle aged people. Evidence is mounting that an osteotomy is not only useful in relieving pain in the symptomatic person but also can prevent knee pain in those with deformities. People need to be convinced about this fact.
For more information, medical assessment and medical quote
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