Overview
What Is An Anaplastic Astrocytomas?
Anaplastic astrocytomas are one of two primary forms of high-grade (malignant) astrocytomas, both of which are more common than low-grade astrocytomas. Anaplastic astrocytomas comprise approximately 30 percent of all astrocytomas. High-grade astrocytomas can occur at any age, but they are more common in older patients.
Basic Symptom Description
The most common clinical symptoms presented by patients suffering from Brain Tumors can be summarised in the following list: -
- Constant Headache
- Loss of vision
- Loss of memory (Dimentia) sometimes leading to personality change
- Siezures
- Paralytic condition or change in gait due to loss of natural contol of limbs
Because of the large number of patients that come to us we are able to see the entire range of patients starting from those who present none of these symptoms to those who exhibit almost all of them.
The confirmatory diagnosis is achieved through MRI, CT and PET scans.
The treatment offered by conventional medicine in majority of the cases is surgical removal of the tumor. When the Brain Tumor is diagnoses as malignant, Radiation therapy and Chemotherapy are also used. Even when reccomended it is always expected to have adverse consequences. However, these forms of treatment are not usually recomended for low grade Brain Tumors.
Diagnosis
These tumors are diagnosed with imaging studies and tumor biopsy. Currently, magnetic resonance imaging (MRI) is the best available imaging modality. Computed tomography (CT) scans also are used. For either study, an agent that provides contrast in the image is administered intravenously so neurological surgeons can visualize the tumor against the normal brain in the background. In some cases, neurological surgeons may employ an MRI scan with frameless stereotactic guidance.
For this study, a contrast MRI is performed after special markers (called fiducials) are placed on the patient's scalp. The fiducials are processed by a computer, which calculates the location of the tumor and creates a three-dimensional reconstruction. This image then is used at the time of surgery to help locate the tumor precisely, maximize tumor removal, and minimize injury to the surrounding brain.
Treatment
High-grade astrocytomas require aggressive, intense therapy. As with other types of astrocytomas, surgery is the primary form of treatment, but its utility is limited because these tumors tend to penetrate healthy brain tissue, making complete resection unlikely and recurrence almost certain. As a result, surgery almost always is followed by radiation therapy, and then chemotherapy. Stereotactic radiosurgery also may be used in cases of tumor recurrence or to target areas missed during the surgical resection.
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