Your Physician may recommend a liver transplant when all other treatment options fail. The purpose is to replace your diseased liver with a healthy liver. Ideally, after a transplant you will be free from disease, and lead a fairly normal life as long as the transplant functions .
Liver transplantation is surgery to remove a diseased liver and replace it with a healthy liver from an organ donor. A liver transplant is necessary when disease makes the liver stop working. The most common reason for liver transplantation in adults is cirrhosis, a disease in which healthy liver cells are killed and replaced with scar tissue. The most common reason for transplantation in children is biliary atresia, a disease in which the ducts that carry bile out of the liver are missing or damaged.
Liver transplantation is usually done when other medical treatment cannot keep a damaged liver functioning. About 80 to 90 percent of people survive liver transplantation. Survival rates have improved over the past several years because of drugs like cyclosporine and tacrolimus that suppress the immune system and keep it from attacking and damaging the new liver.
Indications For liver Transplant Include:
Acute Liver Filure
Due to poisons or Hepatitis Chronic Liver Diseases (Cirrhosis)
Viral Hepatitis Related Liver Tumours There are two primary options for liver donation.
Liver Donation from a patient who has undergone brain death. (Deceased Donor Liver Transplantation, DDLT)
Donation of Part of the liver from another person (Living Donor Liver Transplantation LDLT). At AIMS we perform both DDLT and LDLT, However fisrt degree relatives are preferred as donors for LDLT.
Living-donor transplantation entails the removal of a portion of the donor's healthy liver into another person who is in need of transplantation (recipient). A family member, usually a parent, sibling or adult child (above the age of 18 years) or someone emotionally close, such as a spouse, may volunteer to donate a portion of their healthy liver.
Liver Transplant Symptoms
People Who Have Liver Disease May Have Many Of The Following Problems:
Jaundice - Yellowing of the skin or eyes
Dark, tea-colored urine
Gray- or clay-colored bowel movements
Ascites - An abnormal buildup of fluid in the abdomen
Vomiting of blood
Tendency to bleed
Mental confusion, forgetfulness
Exams And Tests
If a patient comes to the hospital or an emergency department, the doctor will obtain blood tests, liver function tests, blood clotting tests, electrolytes, and kidney function tests. The doctor may also draw blood levels of certain immunosuppressive medications to make sure they are in the right range. If an infection is considered possible, cultures for viruses, bacteria, fungi, and other organisms may be grown. These may be checked for in the urine, sputum, and blood.
A Recipient May Undergo Some Of The Following Tests Before The Transplantation:
Prednisone May Cause The Following Side Effects:
- Increased susceptibility to infection
- Weakened bones (osteoporosis)
- Muscle weakness
- Salt and water retention
- Potassium loss
- Easy bruising
- Stretch marks
- Gastric (stomach) ulcers
- Increased cholesterol and triglyceride levels
- Increased hunger
- Blurred vision
- Rounded face ("chipmunk cheeks")
- Enlarged abdomen
- Inability to sleep
- Mood swings
- Hand tremors (shaking)
- Steroid dependency
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